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Pearl Rejuvenation Media with Dr. Jennifer Pearlman

Listen to recent podcast conversations featuring Dr. Jennifer Pearlman, founder of PearlMD, on female-centric longevity medicine, ovarian health, menopause, PCOS, hormone optimization, precision medicine, and the connection between internal health and regenerative aesthetics.

These interviews bring PearlMD's perspective on women's health into a wider conversation about healthspan: how the ovaries shape metabolic signaling, how the menopause transition affects long-term risk, how PCOS can present through different physiological patterns, and how biomarkers, inflammation, hormones, the exposome, skin health, and regenerative treatments can be understood together. For patients exploring PearlMD in Toronto or Muskoka, the episodes offer a deeper look at Dr. Pearlman's approach to prevention, age management, personalized medicine, aesthetic medicine, and the emerging science of FemSpan.

Female longevity Menopause medicine Ovarian longevity PCOS Hormone optimization Regenerative aesthetics
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The Optispan Podcast with Matt Kaeberlein

The Best Women's Health Tips on the Planet with Dr. Jennifer Pearlman

Dr. Matt Kaeberlein sits down with Dr. Jennifer Pearlman for a deep conversation on why menopause may be one of the most important longevity events in human biology. The episode explores the systemic gaps in women's health, the science and controversy surrounding the Women's Health Initiative, the return of menopause medicine, bioidentical hormone therapy, estradiol as a regenerative signal, progesterone, testosterone for women, ovarian tissue cryopreservation, advanced cardiovascular diagnostics, AI in women's precision medicine, and Pearlman's FemSpan framework for female longevity.

In this conversation
  • Female longevity, FemSpan, and why women's biology needs its own longevity framework.
  • Menopause as a metabolic, hormonal, inflammatory, and regenerative transition.
  • Estradiol, progesterone, testosterone, route of administration, and personalized hormone optimization.
  • Ovarian tissue cryopreservation, regenerative medicine, and the future of female healthspan.
  • AI, biomarkers, cardiovascular diagnostics, and precision medicine at scale.

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